Description
Selank + Semax Blend at a glance
The Selank + Semax Blend puts two separate peptides in one freeze-dried vial: 10 mg of Selank and 10 mg of Semax, for 20 mg in total, not 20 mg of each. No published study of this combined vial was identified, so the evidence below is presented per component.
- Composition: Selank 10 mg + Semax 10 mg in one vial (20 mg total)
- Molecule type: two synthetic seven-residue peptides (TKPRPGP and MEHFPGP)
- Listed price: from $82.50 USD
- Form: freeze-dried (lyophilized) powder; no nasal spray or pre-mixed solution
- Shipping: ships within the US, with free shipping on merchandise over $200 after coupons
- Scope: for laboratory research only
Selank + Semax Blend vial size and price per mg
| Vial size | Listed price (USD) | Price per mg |
|---|---|---|
| 10 mg + 10 mg (20 mg total) | $82.50 | $4.13 (combined peptide) |
Prices are in U.S. dollars at the time of writing; the price beside Add to cart is current, and cart or coupon savings are not promised. For comparison, the standalone 10 mg Selank and Semax vials are each listed at $65.00, so the blend costs less than buying both separately.
Selank + Semax Blend compound profile
| Catalog name | Selank + Semax Blend |
|---|---|
| Nominal amount per vial | 10 mg + 10 mg |
| Declared composition | Selank 10 mg + Semax 10 mg; 20 mg total |
| Molecular description of the mixture | Two distinct peptides: Selank (TKPRPGP) and Semax (MEHFPGP). A blend has no single peptide sequence, molecular formula or molar mass. |
| Molecular reference source | Selank: PubChem CID 11765600; Semax: PubChem CID 9811102 |
| Intended scope | Laboratory research |
The profile states the declared composition and links each component’s reference record; it is not a lot analysis. Because the ratio is fixed at 1:1 by mass, the amount of one peptide cannot be changed without changing the other.
How the Selank + Semax Blend components work in research
Semax derives from an ACTH fragment and Selank is a tuftsin analogue; both end in Pro-Gly-Pro, but their best-documented mechanisms differ. Semax raised brain-derived neurotrophic factor (BDNF) in the rat basal forebrain (Dolotov et al., 2006), while Selank produced frontal-cortex gene-expression changes in male rats that partly resembled those after GABA (Volkova et al., 2016).
The one mechanism measured for both in the same experiment is enzyme inhibition. In human serum tested in vitro, Semax and Selank each inhibited enkephalin-degrading enzymes, with IC50 values of about 10 µM and 20 µM respectively (Kost et al., 2001). Each was tested alone, so the assay says nothing about interaction in a mixture.
Key Selank + Semax Blend studies (by component)
| Year | Study & model | What was measured | Main finding | Source |
|---|---|---|---|---|
| 2001 | Kost et al. (each tested separately); human serum | Enkephalin-degrading enzyme inhibition | Both inhibited; IC50 ≈ 10 µM (Semax), 20 µM (Selank) | Bioorg Khim |
| 2006 | Dolotov et al. (Semax); rat basal forebrain | Binding, BDNF protein | Specific binding and higher BDNF | J Neurochem |
| 2008 | Zozulia et al. (Selank); 62 patients with anxiety disorders | Anxiety scales vs medazepam | Similar anxiety-scale effects to medazepam | PubMed |
| 2018 | Lebedeva et al. (Semax); 24 healthy adults, 13 women | Resting-state fMRI | Larger rostral default-mode subcomponent | Bull Exp Biol Med |
| 2020 | Panikratova et al. (each, separate groups); 52 healthy adults | Amygdala connectivity (fMRI) | Shared and peptide-specific connectivity effects | Dokl Biol Sci |
Panikratova’s 2020 study comes closest to the blend question. Fifty-two healthy adults received Selank, Semax or placebo in separate groups, and scans showed right amygdala–temporal connectivity differences. The authors described both shared and peptide-specific effects, but no participant received both peptides together (source). The blend therefore inherits two separate evidence bases, not a combined one.
Selank + Semax Blend research involving women
No study of the combined vial, in women or anyone else, was identified. The women-related data that exist belong to Semax alone: 67 of 110 participants in Gusev’s post-stroke cohort (source) and 13 of 24 in Lebedeva’s imaging study (source) were women, without separate results reported for them. Selank’s clinical abstract gives no sex counts. The gap is twofold: no blend data and no sex-specific results.
Selank + Semax Blend vs separate Semax and Selank vials
| Compound | Type | Main research focus | Sizes on Ellepeptides |
|---|---|---|---|
| Selank + Semax Blend | Two heptapeptides, fixed 1:1 by mass | No study of the mixture; evidence is per component | 10 mg + 10 mg |
| Semax | Heptapeptide; ACTH(4–7) + Pro-Gly-Pro | BDNF signaling, ischemia models, brain-network imaging | 5 mg, 10 mg |
| Selank | Heptapeptide; tuftsin analogue | Anxiety-scale comparison, GABA-related gene expression | 5 mg, 10 mg |
Separate vials let a protocol vary each peptide independently or run single-compound control arms. The blend suits designs that call for a fixed 1:1 mixture in one vial.
Handling, storage and reconstitution math
The blend is one freeze-dried solid containing both peptides. Follow the label for storage of the sealed vial and any prepared solution. Keep it closed and dry, and label any prepared vial with solvent and date.
For a two-component vial, do the arithmetic twice. Total concentration is 20 mg divided by solvent volume, and each component is half of that. In 4.0 mL, the total is 5 mg/mL, made up of 2.5 mg/mL Selank and 2.5 mg/mL Semax. The peptide calculator handles the total, and bacteriostatic water (30 mL) is listed for laboratories that use a preserved diluent.
Ordering the Selank + Semax Blend in the US
Ellepeptides ships the Selank + Semax Blend to addresses within the United States. Shipping is free when the merchandise subtotal exceeds $200 after coupon discounts (before taxes and shipping); below that, standard shipping is $15.99 per order. Available payment methods and delivery options are shown at checkout. Current details are in the shipping policy.
Selank + Semax Blend FAQ
What is in the Selank + Semax blend?
Each vial lists 10 mg of Selank and 10 mg of Semax as freeze-dried powder, for 20 mg of total peptide. Selank is a tuftsin analogue (TKPRPGP) and Semax is an ACTH(4–7) analogue (MEHFPGP). The two remain distinct molecules inside the mixture.
Is it 20 mg of Selank and 20 mg of Semax?
No. The 20 mg figure is the combined total. The vial lists 10 mg of each peptide, which is the same amount as one standalone 10 mg Selank vial plus one standalone 10 mg Semax vial. Calculations for each component should use 10 mg, not 20 mg.
Has the Selank and Semax stack been studied?
Not as a combination in the sources reviewed. The closest work, Panikratova’s 2020 imaging study, gave each peptide to a separate group of healthy adults, and Kost’s enzyme assay tested each separately. No study of a combined vial or of both peptides given together was identified.
Is the blend better than separate Selank and Semax vials?
No study has compared them; the difference is practical. Separate vials allow independent amounts and single-compound controls, while the blend gives a fixed 1:1 ratio in one vial. At the time of writing, both routes cost almost the same.
Do you sell Selank Semax nasal spray in the US?
No. Ellepeptides lists the blend only as freeze-dried powder in a sealed vial, and it does not sell nasal sprays, drops or spray bottles. Published human studies of each peptide used their own formulated preparations, not freeze-dried research vials like this one.
How much does the Selank + Semax blend cost?
The blend is listed at $82.50 USD at the time of writing, which is about $4.13 per mg of combined peptide. The current price appears beside Add to cart, and free shipping applies when the merchandise subtotal exceeds $200 after coupons.
What side effects have studies reported for the blend?
None, because no study of the blend was identified. The component studies reviewed here also do not report detailed adverse-event data in their accessible abstracts. No side-effect profile can therefore be stated for the mixture or reliably summarised for either peptide on this page.
How should the Selank + Semax blend be stored?
Follow the storage conditions printed on the vial label for both the sealed vial and any prepared solution. As general laboratory practice, freeze-dried peptides are kept sealed, dry and away from heat and light. Contact [email protected] if the label leaves a question open.
Is the Selank + Semax blend studied in women?
Not as a blend. The women-related data come from Semax studies alone, where women made up most participants but no separate results were reported, and the Selank clinical abstract gives no sex counts. Ellepeptides is a women-focused brand, but this vial is a research material, not a women’s product.
Where can I buy the Selank + Semax blend in the US?
You can order it from Ellepeptides on this page; vials ship to US addresses, and shipping is free over $200 after coupons. Other blends appear in the Peptide Blends category, and single compounds in Focus, Mood & Sleep.
Selank + Semax Blend references
- PubChem (NCBI). Selank, CID 11765600. PubChem
- PubChem (NCBI). Semax, CID 9811102. PubChem
- Kost NV, et al. (2001). Enkephalinase inhibition by Semax and Selank. Bioorg Khim. PubMed 11443939
- Dolotov OV, et al. (2006). Semax and BDNF in rat forebrain. J Neurochem. PubMed 16635254
- Zozulia AA, et al. (2008). Selank vs medazepam in anxiety disorders. PubMed 18454096
- Volkova A, et al. (2016). Selank and GABA-related gene expression in rats. PMC4757669
- Gusev EI, et al. (2018). Semax and BDNF after ischemic stroke. PubMed 29798983
- Lebedeva IS, et al. (2018). Semax and the default mode network. Bull Exp Biol Med. DOI
- Panikratova YR, et al. (2020). Functional connectomics of Selank and Semax. Dokl Biol Sci. PubMed 32342318
Related research materials: Peptide Blends, Focus, Mood & Sleep peptides, Semax, Selank, Pinealon and our research and sourcing notes. For laboratory research only. Not for human or veterinary use.
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